Two costly mistakes from Inter players proved decisive at the Bernabéu, though the Nerazzurri pushed hard for a leveller that never came.
Chicago Fire welcome Inter Miami to Soldier Field on Thursday, with five points separating third from second in Major League Soccer's Regular Season.
D. Maldini's first-half goal was enough for Cagliari to beat Lecce 1-0 at Unipol Domus in Serie A Matchday 3.
Real Madrid host Inter in the UEFA Champions League League Stage on Tuesday, with both sides yet to register a point in the competition.
